Chemometrics is the science of extracting information from chemical systems by data-driven instrumentation. It is based on statistical tools and targets the elaboration of chemometric models which make the link between a Raman spectrum (raw measured data) and the concentrations of the compounds inside the analyzed medium. They are trained on the basis of reference measurements to be performed on example batches. This step is also called multivariate calibration of the sensor.

A good knowledge of these tools allows to extract rich and precise information. With ProCellics™, RESOLUTION Spectra Systems took up the challenge to make it easy to build robust chemometric models dedicated to bioprocesses.

Principal Component Analysis (PCA): qualitative analysis

Principal Component Analysis: qualitative analysis

Extracting useful information from Raman spectra: multivariate calibration